An Unusual Immunohistochemical Profile (CK7+/CK20-) for Merkel Cell Carcinoma
نویسندگان
چکیده
منابع مشابه
Merkel cell carcinoma with an unusual immunohistochemical profile
The clinical and morphological picture of Merkel cell carcinoma (MCC) may be rather challenging; therefore, the immunohistochemical profile plays a relevant role in confirming the microscopic diagnosis. A panel of antibodies including cytokeratins 20, 7 and epithelial membrane antigen, and neuron-specific enolase is used in confirming the morphological diagnosis of MCC. The majority of MCCs exp...
متن کاملAn Unusual Presentation of Merkel Cell Carcinoma
Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neoplasm of neuroendocrine cells with a predilection for the head and neck and distal extremities in elderly patients. It is principally a disease of the Caucasian race with an incidence of 0.44 per 100,000 and is very high (8%) among immunsuppressed patients (1, 2). The disease course is difficult to predict and ranges from relativel...
متن کاملBasaloid Squamous Cell Carcinoma: An Unusual Ball-Valve Laryngeal Obstruction
Introduction: A rare case of basaloid squamous cell carcinoma (BSCC) of the larynx, which has not been previously reported, is described. Case Report: A 60-year-old man was presented to the Otolaryngology Department with progressive dyspnoea and dysphagia to solids for over a period of 1 week. Direct laryngoscopy revealed a tumour at the laryngeal aspect of the epiglottis, which prolapsed into...
متن کاملMerkel cell carcinoma in an immunosuppressed patient*
Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years. Recognized risk factors are ultraviolet sunlight exposure, immunosuppression, and, more recently, Merkel cell polyomavirus. We report a case of Merkel cell carcinoma in a young HIV positive...
متن کاملMerkel Cell Carcinoma: An Update and Immunotherapy
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with frequent metastasis and death. MCC has a mortality rate of 30%, making it more lethal than malignant melanoma, and incidence of MCC has increased almost fourfold over the past 20 years in the USA. MCC has long been considered to be an immunogenic cancer because it occurs more frequently in immunosuppressed patients from organ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2015
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/144.suppl2.270